



The following pharmacological effects of Cordyceps have been studied by either animal models and/or human (clinical) trials:
• IMMUNOMODULATION: Cordyceps sinensis (CS) can significantly enhance the immunity of the body.
• ANTI-CANCER AND ANTI-MICROBIAL EFFECTS: Associated with immunomodulatory function, CS shows an anti-cancer effect, and was reported to inhibit viral, bacterial and fungal infections.
...• ANTIDIABETIC ACTIVITY: Polysaccharide in CS was reported to significantly lower blood glucose levels.
• ENERGY METABOLISM AND PERFORMANCE ENHANCEMENT: CS was reported to stimulate hepatic energy metabolism. • RESPIRATORY AND PULMONARY FUNCTIONS: CS was reported to relax the bronchial walls as well as having sedative, antitussive, and antiinflammatory properties, thus it is effective against cough, phlegm, asthma and other respiratory ailments. • CHOLESTEROL AND LIPID METABOLISM: The report indicated plasma triglyceride, "bad cholesterol" such as LDL-c and vLDL-c, and total cholesterol levels were lowered by CS.
• EFFECTIVE ON RENAL DISORDER: There are indications that CS may be of use in the treatment of Berger's disease (IgA nephropathy). • EFFECTIVE ON SEXUAL DYSFUNCTIONS AND REPRODUCTIVE DISORDER: Clinical improvement of impotence by taking CS was reported.
• OTHERS: The reports suggested that CS can stimulate erythropoiesis in mouse bone marrow, and inhibits platelet aggregation.
In addition, the compound cordycepin has been extensively studied and has been shown to have anti-tumour and antifungal properties. In one study, it was shown that cordycepin can inhibit nucleolar RNA synthesis in RNA cell (Siev et a/., 1969)
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